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GenoPak Geno Pure Cell Premarable Cell Impremarable
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  Paclitaxel  [Taxol]
 
Catalog Number
1195
25 mg
33069-62-4
853.92
C47H51NO14
 
 
 
  $85.00/Unit
Qty:
 
  Certificate of Analysis
 
  Material Safety Data Sheet
Comments :
No animal source
Storage :

Protect from light and moisture; Store at -20oC

Analytical Data :

≥99% by HPLC,, Soluble in DMSO, CH3OH and EtOH

Synonym :
[Taxol equivalent] ,, [Baccatin III N-benzyl-beta-phenylisoserine ester]
Application :

Antitumor and antileukemic agent isolated from the bark of the yew tree, Taxus brevifolia. An anti-tumor agent that binds to the N-terminal region of b-tubulin and promotes the formation of highly stable microtubles that resists depolymerization, thus preventing normal cell divison and arresting the cell cycle at the G2-M phase.

References :

1; H Parekh, H. Simpkins, Gen. Pharmacol. 29, 167 (1997).-------2; A. Jordan, et.al.,Med. Res. Rev. 18, 259 (1998).-------3; T.H.Wang,et.al., J. Biol. Chem. 274, 8208 (1999).-------4; A.A. Shtil, et.al., Oncogene. 18, 377 (1999)

Paclitaxel  [Taxol]
 
 

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