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  5(6)-Carboxy-2',7'-dichlorodihydrofluorescein diacetate *Mixed isomers* *Cell permeable* [Carboxy-H2DCFDA]
Catalog Number
25 mg
  Certificate of Analysis
  Material Safety Data Sheet
Comments :
No animal source
Storage :
Protect from light and moisture; Store at -20oC
Analytical Data :
Exc: 291 nm in CH3CN / Em: None,, Soluble in DMSO, DMF basic H2O,,, ≥97% by HPLC
Synonym :
5(6)-Carboxy-2',7'-dichlorodihydrofluorescein diacetate
Application :
Fluorogenic probe for detection of reactive oxygen intermediates in neutrophils and macrophages. Cell-permeable H2DCFDA may also be useful for assessing the overall oxidative stress in toxicological phenomena.
References :
1; Fujisawa S, Atsumi T, Ishihara M, Kadoma Y. Anticancer Res 24, 563-9 (2004).------2; Gao F, Yi J, Yuan JQ, Shi GY, Tang XM. Cell Res 14, 81-5 (2004).------3; O'Malley YQ, Reszka KJ, Britigan BE. Free Radic Biol Med 36, 90-100 (2004).-------4; Shiflett SL, Ward DM, Huynh D, Vaughn MB, Simmons JC, Kaplan J. J Biol Chem 279, 10982-90 (2004)
5(6)-Carboxy-2',7'-dichlorodihydrofluorescein diacetate *Mixed isomers* *Cell permeable* [Carboxy-H2DCFDA]

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