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  2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, hydrochloride [MCLA]
Catalog Number
5 mg
  Certificate of Analysis
  Material Safety Data Sheet
Comments :
No animal source
Storage :

Protect from light and moisture; Store at -20oC

Analytical Data :

Exc: 430 nm / Em: 549 nm in CH3OH, Soluble in DMSO, DMF and H2O,,, ≥99% by HPLC and TLC

Synonym :

[2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one Hydrochloride] ,, [Cypridina Luciferin methoxy-analogue ]

Application :
Generation of chemiluminescence by reaction with super oxide O2 or singlett oxygen. Used in research of leucocyte function.
References :

1; Enhanced chemiluminescence of 6-(4-methoxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one by attachment of a cyclomaltooligosaccharide (cyclodextrin). Attachment of cyclomaltononaose (delta-cyclodextrin)." Teranishi K, Nishiguchi T, Ueda H. Carbohydr Res 338, 987-93 (2003).------2; The ability of neonatal and maternal erythrocytes to produce reactive oxygen species in response to oxidative stress." Kondo M, Itoh S, Kusaka T, Imai T, Isobe K, Onishi S. Early Hum Dev 66, 81-8 (2002) .--------3; Superoxide production in the islet of Langerhans detected by the MCLA chemiluminescence method." Sakurai T, Terakawa S. Methods Mol Biol 196, 203-9 (2002)

2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, hydrochloride [MCLA]

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