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  5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt  [EDANS]
Catalog Number
1 g
  Certificate of Analysis
  Material Safety Data Sheet
Comments :
No animal source
Storage :
Protect from light ; Store at room temperature
Analytical Data :
Exc: 336 nm / Em: 491 nm in buffer pH 8,, Soluble in DMSO, DMF and H2O,,, ≥98% by HPLC
Synonym :
[1-Naphthalenesulfonic acid, 5-((2-aminoethyl)amino)-, monosodium salt] ,, [N-(Aminoethyl)-5-naphthylamine -1-sulfonic acid]
Application :
Fluorescent probe for peptide analysis, sequencing and synthesis. EDANS is one of the most common fluorophore that could be used by pairing with Dabcyl quencher [Genolite #1078] for making fluorescence resonance energy transfer probes [FRET].
References :
1; Substrate recognition through a PDZ domain in tail-specific protease." Beebe KD, Shin J, Peng J, Chaudhury C, Khera J, Pei D. Biochemistry 39, 3149-3155 (2000).--------2; A bifunctionalized fluorogenic tetrasaccharide as a substrate to study cellulases." Armand S, Drouillard S, Schulein M, Henrissat B, Driguez H. J Biol Chem 272, 2709-2713 (1997).--------3; A continuous fluorescence-based assay of human cytomegalovirus protease using a peptide substrate." Holskin BP, Bukhtiyarova M, Dunn BM, Baur P, de Chastonay J, Pennington MW. Anal Biochem 227, 148-155 (1995)
5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt  [EDANS]

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