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  4',6-Diamidino-2-phenylindole, dilactate [DAPI, dilactate]
Catalog Number
10 mg
  Certificate of Analysis
  Material Safety Data Sheet
Comments :
No animal source
Storage :
Protect from light and moisture; Store at - 20oC
Analytical Data :
Exc: 348 nm / Em: 457 nm in CH3OH,,Soluble in DMSO, H2O and CH3OH,,, >98% by HPLC
Synonym :
Indole-6-carboxamidine, 2-(p-amidinophenyl)-, dilactate
Application :
DAPI dilactate is more water soluble than DAPl dihydrochloride and is better used for microinjection. DAPI is a very sensitive dye that could be used to detect single nucleic acid molecules. DAPI has been shown to detect a single DNA molecule in solution, and to detect femtograms of DNA in single cells and chloroplasts.
References :
1; Inheritable histone H4 acetylation of somatic chromatins in cloned embryos." Wee G, Koo DB, Song BS, Kim JS, Kang MJ, Moon SJ, Kang YK, Lee KK, Han YM. J Biol Chem 281, 6048-57 (2006).--------2; Spreading of embryologically distinct urothelial cells is inhibited by SPARC." Hudson AE, Feng WC, Delostrinos CF, Carmean N, Bassuk JA. J Cell Physiol 202, 453-63 (2005).-------3; Alternative lengthening of telomeres is characterized by high rates of telomeric exchange." Londono-Vallejo JA, Der-Sarkissian H, Cazes L, Bacchetti S, Reddel RR. Cancer Res 64, 2324-7 (2004)
4',6-Diamidino-2-phenylindole, dilactate [DAPI, dilactate]

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