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GenoPak Geno Pure Cell Premarable Cell Impremarable
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  1,2-Bis(2-Amino-5-fluorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl) ester  *Cell permeable* [5',5-difluoro BAPTA, AM]
 
Catalog Number
1142
25 mg
128255-42-5
800.37
C34H38F2N2O18
 
 
 
  $85.00/Unit
Qty:
 
  Certificate of Analysis
 
  Material Safety Data Sheet
Comments :
No animal source
Storage :
Protect from moisture; Store at -20oC
Analytical Data :
Exc: 292 nm in CH3OH / Em: None,, Soluble in DMSO, DMF, EtOAc, CH3CN and CHCl3,,, ≥98% by HPLC and TLC
Synonym :
Glycine, N,N'-[1,2-ethanediylbis[oxy(4-fluoro-2, 1-phenylene)]]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-, bis[(acetyloxy)methyl] ester
Application :
A cell membrane permeable form of BAPTA which can be loaded into the cell where it is hydrolysed by cytosilic esterases and trapped as the active chelator.It is used for NMR study of calcium in live cells and tissue.
References :
1; L.A. Jelicks, R.K. Grupta., J. Biol. Chem. 265, 1394 (1990).-------- 2; E. Marban, et.al., Proc. Natl. Acad. Sci. USA 84, 6005 (1987).--------- 3; R.S. Badar-Goffer, et.al., J. Neurochem. 55, 878 (1990).-------- 4; G.A.Smith et.al., Proc Natl. Acad.Sci. USA. 80,7178 (1983).-------- 5; E. Marban et.al., Circ. Res. 66, 1255 (1990).
1,2-Bis(2-Amino-5-fluorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl) ester  *Cell permeable* [5',5-difluoro BAPTA, AM]
 
 

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