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  3-Maleimidopropionate, succinimidyl ester [N-Succinimidyl 3-maleimidopropionate] ,, [BMPS]
Catalog Number
100 mg
  Certificate of Analysis
  Material Safety Data Sheet
Comments :
No animal source
Storage :

Protect from light and moisture; Store at -20oC

Analytical Data :

≥97% by HPLC and TLC,, Soluble in DMSO, DMF, CH3CN and CHCl3

Synonym :

[1H-Pyrrole-2,5-dion, 1-[3-[(2,5-dioxo-1-pyrrolodinyl)oxy]-3-oxopropyl],,[β-malemidopropinic acid N-hydroxysuccinimide ester] ,, [[Maleoyl-β-alanine N'-hydroxysuccinimide ester] ,, [N-(3-maleimodopropionyloxy)succinimide]

Application :

An important cross-linking reagent with amine and sulfhydryl reactivity for the preparation of protein-protein and peptide-protein conjugates linked by disulfide bonds. It is also useful for the preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Acylation at pH 8 proceeds most selectively whereas the stability of the maleimido group is much better compared to aromatic derivatives .

References :

1; Kitagawa, T., et.al., Chem. Pharm. Bull. 29, 1130 (1981).-------- 2; L. Moroder, et.al., Biopolymers 22, 481 (1983).------- 3; H. Tanimori, et.al., J. Immunol. Methods 62, 123 (1983).-------- 4; S. Hashida, et.al., J. Appl. Biochem. 6, 56 (1984).-------- 5; S. Inoue, et. Al., Annal. Lett. 17,229 (1984);

3-Maleimidopropionate, succinimidyl ester [N-Succinimidyl 3-maleimidopropionate] ,, [BMPS]

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