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  5(6)-Carboxy-2',7'-dichlorofluorescein *Mixed isomers*  [CDCF]
Catalog Number
100 mg
  Certificate of Analysis
  Material Safety Data Sheet
Comments :
No animal source
Storage :
Protect from light and moisture; Store at room temperature
Analytical Data :
Exc: 505 nm / Em: 530 nm in CH3OH, buffer pH 9,, Soluble in DMSO, DMF, CH3OH and basic H2O,,, ≥98% by HPLC
Synonym :
Spiro(isobenzofuran-1(3H),9'-(9H) xanthene)-ar-carboxylic acid, 2',7'-dichloro-3',6'-dihydroxy-3-oxo-
Application :
Fluorescent probe for fluid phase markers of endocytosis.
References :
1; Use of the anionic dye carboxy-2',7'-dichlorofluorescein for sensitive flow cytometric detection of multidrug resistance-associated protein activity." Laupeze B, Amiot L, Courtois A, Vernhet L, Drenou B, Fauchet R, Fardel O. Int J Oncol 15, 571-576 (1999).------ 2; Structural transitions associated with the interaction of Alzheimer beta-amyloid peptides with gangliosides." McLaurin J, Franklin T, Fraser PE, Chakrabartty A. J Biol Chem 273, 4506-4515 (1998).------- 3; Membrane disruption by Alzheimer beta-amyloid peptides mediated through specific binding to either phospholipids or gangliosides. Implications for neurotoxicity." McLaurin J, Chakrabartty A. J Biol Chem 271, 26482-26489 (1996).
5(6)-Carboxy-2',7'-dichlorofluorescein *Mixed isomers*  [CDCF]

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