10:50:AM | Mon, Jun 24, 2019
GenoPak Geno Pure Cell Premarable Cell Impremarable
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  Fluo-2, AM  *Cell permeable*  *1 mM/anhydrous DMSO* *GenoSol* 
Catalog Number
1 ml
  Certificate of Analysis
  Material Safety Data Sheet
Comments :
No animal source
Storage :
Protect from light and moisture; Store at -20oC
Analytical Data :
Exc: 506 nm / Em: 526 nm in 0.1 M Tris buffer pH 8.0,, Soluble in DMSO, DMF, CH3CN, EtoAc and CHCl3
Synonym :
4-(6-Acetoxymethoxy-2,7-dichloro-3-oxo-9-xanthenyl)-4′-methyl-2,2′(ethylenedioxy)dianiline-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl) ester
Application :
Cell permeable fluorescent indicator of intracellular Ca2+; non-fluorescent until it is hydrolyzed intracellularly and/or in the presence of Ca2+; lower binding affinity allows measurement of higher peaks of Ca2+ transients than with Fura-2 (Genolite's  1100)
References :
1; J.P.Y. Kao, Detection of photochemically generated calcium pulses. J. Biol. Chem. 264, 8179, (1989).--------2; Koncz A, Pasztoi M, Mazan M, Fazakas F, Buzas E, Falus A, Nagy G,  J Immunol 2007; 179(10):6613-9.--------3Kamioka H, Sugawara Y, Murshid SA, Ishihara Y, Honjo T, Takano-Yamamoto T, J Bone Miner Res 2006; (21):7 1012-1021

Fluo-2, AM  *Cell permeable*  *1 mM/anhydrous DMSO* *GenoSol*

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