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  Bis-(3-phenyl-5-oxoisoxazol-4-yl)pentamethine oxonol  [oxonol V]
Catalog Number
100 mg
  Certificate of Analysis
  Material Safety Data Sheet
Comments :
No animal source
Storage :
Protect from light and moisture; Store at room temperature
Analytical Data :
Exc: 610 / Em: 640 in CH3OH,, Soluble in DMSO, DMF, CH3OH, CH3CN and EtOH,,, ≥99% by HPLC
Synonym :
5(4H)-Isoxazolone, 4-(5-(5-hydroxy-3-phenyl-4-isoxazolyl)-2,4-pentadienylidene)-3-phenyl-
Application :
Potential sensitive probe as an optical indicator for membrane potentials in lipid vesicles
References :
1; Ratiometric fluorescence measurements of membrane potential generated by yeast plasma membrane H(+)-ATPase reconstituted into vesicles." Holoubek A, Vecer J, Opekarova M, Sigler K. Biochim Biophys Acta 1609, 71-9 (2003).-------2; The Escherichia coli multidrug transporter MdfA catalyzes both electrogenic and electroneutral transport reactions." Lewinson O, Adler J, Poelarends GJ, Mazurkiewicz P, Driessen AJ, Bibi E. Proc Natl Acad Sci U S A 100, 1667-72 (2003).-------3; Proton-motive force stimulates the proteolytic activity of FtsH, a membrane-bound ATP-dependent protease in Escherichia coli." Akiyama Y. Proc Natl Acad Sci U S A 99, 8066-71 (2002).-------4; Anomalous response of oxonol-V to membrane potential in mitochondrial proton pumps." Ahmed I, Krishnamoorthy G. Biochim Biophys Acta 1188, 131-138 (1994)
Bis-(3-phenyl-5-oxoisoxazol-4-yl)pentamethine oxonol  [oxonol V]

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